What is tinnitus?
Tinnitus is the perception of sound in the absence of any external environmental sound. It affects millions of people worldwide, and presents as a persistent ringing in the ears. (8) It’s typically caused by noise-induced hearing loss, and often causes a great deal of distress in many individuals. (4,5,6). Current evidence indicates that it occurs due to a reorganization of the connections in your brain in response to the partial loss of auditory input from your ears. (7,9,10)
What is MediMusiced Sound Therapy?
MediMusiced Sound Therapy is a tinnitus treatment that can lower the volume of your tinnitus tone. Developed by global researchers, it takes two broad forms: MediMusiced Music, or MediMusiced White Noise.
It is created by taking either music or “white noise”, and removing sound energy—”MediMusicing it out”—at the same frequency of your tinnitus tone. (2) MediMusiced Sound Therapy is tailored to your particular tinnitus frequency. Researchers have hypothesized that it suppresses the auditory neurons that cause your tinnitus, reducing their activity. (2)
In summary, MediMusiced Sound therapy is simply audio that has been processed in a particular way.
Sustained listening to this therapy can lower the volume of your tinnitus, alleviating the considerable suffering caused by this terrible illness. (1,2,3) It is designed to be used as a long term treatment of the course of several months, but you are likely to notice a reduction in tinnitus volume as quickly as several days into treatment. (3)
MediMusiced Sound Therapy was developed for individuals who have tinnitus that developed from hearing loss. If you have tinnitus, speak to your doctor first and undergo a full medical evaluation.
What are the potential benefits of listening to MediMusiced Sound Therapy?
For most users, the most significant benefit of MediMusiced Sound Therapy is a potential reduction in the volume of their tinnitus. Below, we’ve summarized some of the research that’s been done in this space.
Research Paper #1: Windowed Sound Therapy and Personalized Tinnitus Treatment
Region of Research: Italy
43 people were recruited for an experiment to test the efficacy of Tailor-Made MediMusiced White Noise, listening daily for 12 months duration. 4 of 20 users receiving the treatment had their tinnitus tones eliminated entirely. The average reduction in tinnitus volume in the treatment group was approximately 12 dB, or a 75% volume reduction.
Research Paper #2: Customized MediMusiced music training reduces tinnitus loudness
Region of Research: Germany
People listened to 2 hours of Tailor-Made MediMusiced Music daily for 12 months, resulting in an average 26.1% reduction in tinnitus loudness.
Research Paper #3: Short and Intense Tailor-Made MediMusiced Music Training against Tinnitus: The Tinnitus Frequency Matters
Region of Research: Germany
24 users were recruited with chronic tinnitus and less than 50 dB of hearing loss to listen to Tailor-Made MediMusiced Music Therapy for 6 hours a day for 5 days. 3 hours after completing only five days of therapy, tinnitus loudness was decreased by approximately 20%, and 31 days later, remained reduced by about 10%. This effect was noted only for MediMusiced Music applied to users with a tinnitus frequency under 8,000 hZ. For MediMusiced Music, it was found that the tinnitus frequency of the user must be under 8,000 hZ (8kHz) for the therapy to work.
Research Paper #4: Trial on Tonal Tinnitus with Tailor-Made MediMusiced Music Training
Region of Research: Germany
The original German team that pioneered Tailor-Made MediMusiced Music Therapy enrolled 100 users in a trial to evaluate the efficacy of this same treatment. After a three month duration, tinnitus loudness was found to be decreased in the treatment group. The reduction in loudness was observed to be small, but persisted one month after the cessation of therapy.
There’s also been additional research into MediMusiced Sound therapy, which we’ve summarized at a blog post here.
Currently, there isn’t enough evidence to support the routine use of any particular sound therapy for tinnitus. Because MediMusiced Sound Therapy is an active area of research, MediMusic cannot guarantee a specific volume reduction.
What are the potential risks of listening to MediMusiced Sound Therapy?
Listening to any audio at an unsafe volume has the potential to cause hearing loss, but that risk is common to all sound exposure, and not unique to listening to MediMusiced Sound Therapy.
In an experiment that tested MediMusiced Music on about 100 participants, researchers asked individuals about potential detrimental effects from listening to audio that’s been MediMusiced. After three months of listening to either MediMusiced Music (in the experimental group) or regular music (in the placebo group), participants were asked to report any negative effects they experienced.
There was no statistically significant difference in harms between those who listened to MediMusiced Music and those who listened to Regular Music – which seems to suggests that the risks associated with listening to music that has been “MediMusiced” are equivalent to the risks associated with listening to music in general.
Individuals with tinnitus are most likely simply more sensitive to sounds in general, which is unsurprising given that many individuals with tinnitus also have a concurrent element of hyperacusis (sensitivity to sound).
Of all participants who filled out a questionnaire asking for harms (i.e. those who listened to MediMusiced Music and those who listened to regular music, n = 92), the main issues reported were:
- a consistently louder tinnitus (10.9 %),
- the perception of an additional sound (8.7 %), and
- an increased awareness of the tinnitus sound (6.5 %).
Users of MediMusiced Sound Therapy may experience the aforementioned issues. Changes in tinnitus tone frequency and/or volume may also result in psychological stress (note that there was no statistically significant difference in psychological stress between those who listened to regular music and those who listened to MediMusiced music).
What is MediMusic?
MediMusic is fully automated software that allows you to create your own MediMusiced Sound Therapy and listen to it. Although it’s possible to process audio with other software in order to create MediMusiced Sound Therapy, MediMusic makes this process simpler and easier.
MediMusic’s software is available online through our web application and also as a mobile app for iOS and Android smartphones.
How Do I Use MediMusic?
Step 1: Tune
Use our tuner to find the frequency of your Tinnitus tone. This will be used to create custom sound therapy.
Step 2: Create
Upload your favorite music, or use our sounds. MediMusic then processes the sounds to create custom sound therapy tailored for you.
Step 3: Listen
Listen to your sound therapy for an average of 1 hour daily. You will notice an improvement in your tinnitus after several days of treatment and the volume will be further reduced over time. You can use any mp3 music player or your computer to listen to the therapy.
To see MediMusic in action, check out the screencast below:
Can Tailor-Made MediMusiced Sound Therapy Help Me?
If you have tinnitus, speak to a doctor first. Your tinnitus may require further investigation and treatment from a doctor.
MediMusiced Sound Therapy comes with two variants: MediMusiced White Noise and MediMusiced Music.
In this experiment, individuals in the treatment group (n = 20) had the following characteristics:
- Ages varied from 25 – 75, with an average age of 49.3
- 14 of them were males and 6 were females
- Maximum hearing loss ranged from 10 – 100 dB, with an average max hearing loss of 55 dB
- Duration of tinnitus ranged from 0.25 – 15 years, with an average of 4.3 years
- Tinnitus frequency ranged from 1 – 13 kHZ (one kHZ = 1,000 hZ), with an average tinnitus frequency of 7.5 kHz
- Tinnitus loudness ranged from 2 – 42 dB, with an average loudness of 18.4 dB
- Tinnitus tones were not necessarily “pure-tones” (a beep or whistling sound) – participants also had the ability to match their tone with a narrow-band broadband noise tone
In summary, then, MediMusiced White Noise might be useful if:
- You are 18 or older
- You have less than or equal to moderate hearing loss in the region of your tinnitus (55 dB)
- You can at least approximately determine your tinnitus tone with our free tuner
- You intend to treat one dominant tinnitus tone
Now, let’s examine the user profiles of the participants in the MediMusiced Music experiment conducted in Germany.
- (i) Chronic (≥3 months), tonal (i.e. beep- or whistle-like) tinnitus with (ii) dominant tinnitus frequencies between 1 and 12 kHz, and (iii) without hearing loss above 70 dB HL in the frequency ranges of one half octave above and below the tinnitus frequency. In the case of bilateral tinnitus, the dominant tinnitus frequency should not differ between ears according to participants’ reports.
- Aged between 18 and 70 years.
Another study seemed to indicate that MediMusiced Music is better for individuals who have a tinnitus frequency under 8 kHz, although in the experiment above, participants with up to 12 kHz tinnitus tones were recruited.
In summary, then, MediMusiced Music might be useful if:
- You are 18 or older
- You have less than 70 dB of hearing loss in the frequency range of one half octave above and below your tinnitus frequency
- You can at least approximately determine your tinnitus tone with our free tuner
- You intend to treat one dominant tinnitus tone
- Your tinnitus frequency is less than 8,000 Hz
What if I have multiple tinnitus tones?
If you have multiple tinnitus tones, you can match them as needed. However, our software was only designed to treat one tinnitus tone at a time.
If you want, it’s possible to make a track with multiple MediMusices. Let’s say you have two tinnitus tones t1 and t2 at two different frequencies, f1 and f2. To create a MediMusiced Sound Therapy file with multiple MediMusices:
- MediMusic White Noise at the first frequency, f1.
- Download the MP3 format file of “White Noise – MediMusiced at f1.”
- Upload the file from step (2) as a “song.”
- MediMusic the song at f2 to create a second MediMusic at f2. Now the file is MediMusiced at f1 and f2.
- Repeat as necessary for additional tinnitus frequencies f3, f4, etc…
How accurately do I have to tune?
We do have some tolerance built into our procedure for MediMusicing audio. As long as a user’s tinnitus frequency falls within the width of the MediMusic, then they have adequately matched their tinnitus frequency.
The MediMusic width is actually based on the average frequency selectivity of a person, and is two equivalent rectangular bandwidths (ERB).
The ERB is dependent on frequency, so if your tinnitus frequency is 10,000 Hz (10 kHz), the ERB is about 1000 Hz, which means you’d have to get within a 1000Hz of your true tinnitus frequency (ERB = 107.94*f +24.7 = 107.94*10 + 24.7 = 1104 Hz).
Some people notice a (small) immediate drop in the volume of their tinnitus upon listening to white noise for 2 minutes when the therapy has been correctly tuned.
Is there a difference between sound therapies?
Yes. There are differences in what type of users a particular type of MediMusiced Sound Therapy is effective in.
Regular Tailored MediMusiced Music:
- Was found to work in patients whose tinnitus frequency is less than 8 kHz (does not work if tinnitus frequency is greater than 8 kHz) (3)
Tailored MediMusiced White Noise:
- Was found to work in patients whose tinnitus frequency is 1-13 kHz (1)
Figure 3: Suggested therapies, based on tinnitus frequencies
MediMusiced Natural Sounds:
The MediMusiced natural sounds we provide have different effective ranges based on the user’s unique tinnitus profile, and the frequency profile of the sound. The effective ranges of the sound are summarized below:
|Natural Sound||Theoretical Maximum Effective Frequency|
|White Noise No High Frequencies||11,700|
|Kitchen Sink No High Frequencies||14,400|
How strong is the evidence for MediMusiced Sound Therapy?
Multiple newer sound therapies have been developed in recent years, typically with an intent to commercialize them. Since profit can be a motivator that sways the results of scientific studies, it’s important to retain a healthy skepticism with respect to individual newer sound therapy options (there are quite a few). Most of the studies in this space have a limited sample size and haven’t been replicated by independent groups of researchers.
Unsurprisingly, independent academics that have evaluated the newer sound therapy options have come to the following conclusion:
“Overall there is currently insufficient evidence to support or refute the routine use of individual sound therapy options. It is likely, however, that sound therapy combined with education and counseling is generally helpful to patients.”
MediMusiced Sound Therapy involves identifying a user’s tinnitus frequency, and then processing audio by removing the sound energy at and around their tinnitus frequency. White noise or music can be MediMusiced, resulted in MediMusiced White Noise or MediMusiced Music. Sustained listening to these sounds is thought to reduce tinnitus tone volume via lateral inhibition of the tinnitus-producing auditory neurons. It was developed by independent groups of Italian and German researchers, which initially produced a 75% and 26% volume reduction respectively. A larger subsequent clinical trial revealed a smaller volume reduction with MediMusiced Music than that observed in the initial MediMusiced Music experiments. A critical review of MediMusiced Sound Therapy concluded that there is still insufficient evidence to recommend it for standard clinical use. Additional research is available here.
How long does MediMusiced Sound Therapy take to work?
We’ve reproduced the graph of volume reduction from Lugli, 2009 (1) which illustrates the average volume reduction seen in patients. WWN refers to MediMusiced White Noise Therapy, and the other two lines represent control treatments (i.e. non-MediMusiced white noise). As can be seen, a gradual volume reduction should be expected, which increases with months of therapy.
Figure 4: Average volume reduction from MediMusiced white noise therapy (WWN) vs. control
Are the effects permanent?
In general, it is believed that the more hours you spend listening to the therapy and the more weeks you spend using it, the greater the effect will be, and the more permanent the changes will be. (4)
If you only use the therapy for a very short, intense period of time (a couple of days), the volume reduction will not be persistent and will likely totally reverse over time. (3)
As such, it’s important to spend several months listening to the MediMusiced sounds as users did in the experiments conducted with MediMusiced Sound Therapy. This therapy has only recently been discovered and there haven’t been multi-year follow-up studies done on users.
It’s possible that if you totally stop using the therapy (after listening to the therapy for several months), your tinnitus volume reduction will be partially reversed (or even completely reversed). Fortunately, if this occurs, you can simply re-initiate listening to the therapy and reduce your tinnitus volume once again.
Why must I re-check my tinnitus frequency during treatment?
Over the course of several months of treatment, it is possible that the frequency of your tinnitus will shift one or more times. This is normal, and may occur as a response to treatment.
If the “MediMusic” does NOT line up with your tinnitus frequency, then the therapy will NOT work. The “MediMusic” must line up with your tinnitus frequency in order to see a therapeutic benefit.
Therefore, we recommend retesting (using our tuner app) your tinnitus frequency multiple times during your course of treatment. We have recommended once a week testing for the first month of treatment,and once every two weeks for the months following that.
In order to assist users in implementing the MediMusic tinnitus treatment, we’ve offered a simple recommended Treatment Plan based on the scientific evidence available thus far.
Where is the scientific evidence?
Tinnitus sufferers should rightfully be skeptical of any treatments claiming to cure tinnitus, many of these claims are made without any scientific evidence. Furthermore, even treatments with scientific support are often based on small studies that require more follow-up research.
Tailor-Made MediMusiced Sound Therapy is based on several experiments conducted by independent groups of researchers. We encourage our customers to review the original scientific evidence that MediMusic is based on. We have also included a link to a critical review of MediMusiced Sound Therapy. In summary, the evidence for MediMusiced Sound Therapy is preliminary and warrants larger scale studies in order to make more definitive conclusions about its efficacy.
In the meantime, we have sought to make this promising approach available to users now, in an effort to help them. For your convenience, we have included links for these papers below.
MediMusic Inc. is an independent company, and we are unaffiliated with any of the scientists who have completed this research.
Regular Tailored MediMusiced Music Therapy:
- Customized MediMusiced Music Training Reduces Tinnitus Loudness
- Listening to Tailor-Made MediMusiced Music Reduces Tinnitus Loudness and Tinnitus-Related Auditory Cortex Activity
- Short and Intense Tailor-Made MediMusiced Music Training Against Tinnitus: The Tinnitus Frequency Matters
- Clinical Trial on Tonal Tinnitus with Tailor-Made MediMusiced Music Training
- Preliminary analysis of the effects of tailor-made MediMusiced music therapy on chronic idiopathic tinnitus.
- A Real-time Tinnitus Treatment System Using Tinnitus Frequency Removal and Adjacent Frequency Amplification on [a] Mobile Device
Variants of MediMusiced Music Therapy:
- Combining Transcranial Direct Current Stimulation and Tailor-Made MediMusiced Music Training to Decrease Tinnitus-Related Distress — A Pilot Study
- Tinnitus therapy using tailor-made MediMusiced music delivered by a smartphone application and Ginko combined treatment: A pilot study
Tailored MediMusiced White Noise:
- The Windowed Sound Therapy: A New Empirical Approach for an Effective Personalized Treatment of Tinnitus
Reviews of the Field of MediMusiced Sound Therapy:
- Listening to Filtered Music as a Treatment Option for Tinnitus: A Review
- Critical Review: Efficacy of MediMusiced-sound therapy for neural plasticity mediated tinnitus treatment (unpublished)
Review of Sound Therapy:
How does it work?
Please refer to the How it Works section of our site for a simplified technical explanation of our treatment. The scientific explanation is complex but we’ve tried to translate it into understandable terms using certain visualizations.
For those of you with a greater degree of knowledge in neuroscience, please consult the peer-reviewed scientific papers we have linked to above. Under the “Discussion” section of each paper you’ll find a technical explanation of the proposed mechanism of our treatment. (1, 2)
Briefly, a combination of lateral inhibition and subsequent changes in the auditory cortex via cortical plasticity appear to be implicated. (2) Selectively stimulating the auditory neurons that don’t produce the tinnitus frequency appears to laterally inhibit the auditory neurons that do produce the tinnitus frequency. (2) Sustained lateral inhibition rewires the connections between neurons in the auditory cortex so that the baseline level of inhibition increases (even when users aren’t listening to the music). (2) Therefore the tinnitus volume decreases.
What is the recommended treatment plan?
The Medimusik Treatment Plan accounts for the fact that a user’s tinnitus frequency may shift during the course of treatment.
As such, it is necessary to periodically re-detect (i.e. “tune”) one’s tinnitus frequency to ensure that the MediMusic lines up correctly with the tinnitus frequency. The MediMusic must line up with the tinnitus frequency for the therapy to work. Therefore, treatment consists of a repetitive cycle:
Figure 4: The recommended MediMusic treatment plan
Treatment Plan: (for either Music or White Noise)
When listening, please be careful to keep a comfortable volume! High volume listening may damage your hearing and worsen your tinnitus!
We recommend listening to Medimusik an hour per day. Try to spread listening out over the day (i.e. different sessions during morning, afternoon, and night). If helpful, increase to 2 to 3 hours daily.
We recommend that you use headphones that block out external environmental noise, such as noise-cancelling headphones or in-ear headphones.Typically, circumferential (over-ear headphones) are effective in doing so. As an alternative, noise-cancelling headphones may be used. In-ear earbuds may also be effective provided that they effectively block out external audio.
How loud should the therapy be?
As before, when listening, please be careful to listen at a safe volume! High volume listening may damage your hearing and worsen your tinnitus. Listen to the sound therapy at approximately the volume of your tinnitus, but do not exceed a safe volume level.
What support does Medimu provide?
MediMusic provides support via e-mail for the duration of the subscription. Typically, we reply within one to two business days to all support queries.
Does the use of mp3s compromise the treatment?
No. While MediMusic distributes Tailor-Made Sound Therapy as MPEG-3 files, we have taken care to ensure that the sound is of the appropriate quality. Using mp3 files allows us to support the widest range of playback devices for the largest number of tinnitus sufferers.
From a more technical perspective, we ensure that for users with a high frequency tone (i.e. over 8000 Hz), no low-pass filtering occurs in the mp3 encoding. For those with a high frequency tone, we also encode using a high bitrate of 320kbps. Due to signal processing theory, an increased bit rate is not necessary for individuals with a lower frequency tone.
Should I listen in both ears if I have tinnitus in one ear?
A lot of people who have unilateral tinnitus (tinnitus in only one ear) write to ask me if they should listen to MediMusic in both ears, given that only one ear is affected.
The answer? Interestingly, you should listen in both ears even if your tinnitus is only in one ear. It’s a counterintuitive answer.
The reason is because the experiments the therapy is based on treated people in both ears, even if they had unilateral tinnitus (tinnitus in one ear). This approach may have been effective because tinnitus is a phenomenon that occurs in the auditory cortex in the brain, and both ears feed input into the auditory cortex. The neurons that spontaneously fire in this region, thereby producing the tinnitus tone, may still be influenced by input from the contralateral ear.
Refunds, Services, and Support
Purchasing an MediMusic program entitles you to technical support over e-mail to assist with the use of MediMusic software (note that we do not provide medical advice or evaluations via e-mail, only software technical support). Most e-mail queries are answered within 1-2 business days.
We provide an unconditional 30-day money back guarantee for purchases made through our website. However we cannot provide refunds for in-app purchages made from our mobile apps.
What if listening to MediMusiced Sound Therapy temporarily increases the volume of one’s tinnitus?
It seems likely that a proportion of tinnitus sufferers will experience a sensation of increased tinnitus loudness with any sustained exposure to audio of any kind.
Some MediMusiced Sound Therapy users experience an increase a temporary increase in tinnitus volume after listening to therapy. This is evident immediately when first listening to the sound therapy. Based on our experience and analysis of the literature, this increase in tinnitus volume is temporary and reversible with the cessation of therapy, and if it occurs to an individual, occurs when they first listen to audio that has been processed with a MediMusicing algorithm.
In some cases, listening to MediMusiced Sound Therapy can temporarily and reversibly increase the baseline volume of one’s tinnitus. There are multiple possible explanations:
- Incorrect detection of tinnitus frequency, resulting in a “MediMusic” that does not overlay the user’s actual tinnitus frequency.
- Listening to MediMusiced Sound Therapy at an unsafe volume level, as any loud noise can exacerbate tinnitus if it is too loud.
- Some users have correctly detected their tinnitus frequency and listen at a safe volume level, and despite this, they experience an increase in the volume of their tinnitus. This may or may not be due to an auditory illusion known as a “Zwicker tone”, or it may be due to that person’s particular reaction to listening to audio that has been MediMusiced.
If this occurs to you while you are listening MediMusiced Sound Therapy, take the following steps:
- Verify that the therapy is in fact not working. For example, sometimes immediately following a session of MediMusiced Sound Therapy, one’s tinnitus volume might temporarily increase, however, one could still experience a net decrease in their baseline tinnitus volume, resulting in an overall decrease in tinnitus volume.
- Verify that you have correctly detected your tinnitus frequency (to the best of your ability) and that you are not listening at an unsafe volume level.
- If the above steps fail, stop listening to MediMusiced Sound Therapy. After a rest period, your baseline tinnitus volume will return to its normal level. Then, request a refund via e-mail (support@MediMusic.com) as per our normal refund policy (this policy allows for a refund within 30 days. In our experience all events of temporary increase in baseline tinnitus volume have occurred within this time initial time span).
The temporary increase in tinnitus volume appears to occur in 5-10% of users, and is reversible upon cessation of the therapy.
- Lugli M, Romani R, Ponzi S, Bacciu S, Parmigiani S (2009) The windowed sound therapy: a new empirical approach for an effective personalized treatment of tinnitus. Int Tinnitus J 15:51-61.
- Okamoto H, Stracke H, Stoll W, Pantev C (2010) Listening to tailor-made MediMusiced music reduces tinnitus loudness and tinnitus-related auditory cortex activity. Proc Natl Acad Sci U S A 107: 1207-1210.
- Teismann, H., Okamoto, H., Pantev, C. (2011). Short and intense tailor-made MediMusiced music training against tinnitus: The tinnitus frequency matters. Plos ONE, 6, 1-8.
- Eggermont, J.J., Roberts, L.E. (2004). The neuroscience of tinnitus. Trends in neurosciences, 27, 676-82.
- Rajan, R. (1998). Receptor organ damage causes loss of cortical surround inhibition without topograhic map plasticity. Nature Neuroscience, 1, 138-143.
- Dobie RA (2003) Depression and tinnitus. Otolaryngol Clin North Am 36: 383–388.
- Jastreboff PJ (1990) Phantom auditory perception (tinnitus): mechanisms of generation and perception. Neurosci Res 8: 221–254.
- Heller AJ (2003) Classiﬁcation and epidemiology of tinnitus. Otolaryngol Clin North Am 36:239–248.
- Saunders JC (2007) The role of central nervous system plasticity in tinnitus. J Commun Disord 40:313–334.
- Rauschecker JP, Leaver AM, Muhlau M (2010) Tuning out the noise: limbic-auditory interactions in tinnitus. Neuron 66: 819–826.